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rat anti-mouse st2 antibody  (Genentech inc)

 
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    Genentech inc rat anti-mouse st2 antibody
    Rat Anti Mouse St2 Antibody, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+anti-mouse+st2+antibody/rat+anti+mouse+st2+antibody/pm39958476-33-1-8
    Average 90 stars, based on 1 article reviews
    rat anti-mouse st2 antibody - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: Fungal symbiont transmitted by free-living mice promotes type 2 immunity.
    Article Snippet: The gut mycobiota is crucial for intestinal homeostasis and immune function.. Yet its variability and inconsistent fungal colonization of laboratory mice hinders the study of the evolutionary and immune processes that underpin commensalism.. Here, we show that Kazachstania pintolopesii is a fungal commensal in wild urban and rural mice, with an exceptional ability to colonize the mouse gastrointestinal tract and dominate the gut mycobiome.

    Article Title: Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease.
    Article Snippet: A rat anti-mouse ST2 antibody was obtained from Genentech and administered every 72 hours by intraperitoneal injection starting 10 days after DOCA-salt initiation and continued through the end of the protocol in C57BL/6J mice (10 mg/kg).



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    Image Search Results


    PA protected against intestinal I/R injury via an IL-33/ST2 signal. (A) IL-33 immunohistochemical staining in the ileum from sham, I/R and I/R + PA mice, scale bar is 100 μm (n = 8). (B, C) Relative mRNA levels of IL-33 and IL-33 receptor (ST2) (n = 8). (D) HE staining, ZO-1, Occludin and Ki67 immunofluorescent staining and IL-33 immunohistochemical staining in WT mice and IL-33 -/- mice, scale bar is 100 μm (n = 8). (E) Pathological damage score in the ileum. (F–H) The relative fluorescence intensity quantification analysis of ZO-1, Occludin and Ki67 in the ileum. (I) The relative mRNA level of Lgr5 in the ileum was measured by quantitative PCR (n = 8). (J) The relative IL-33 intensity quantification analysis in the ileum. (K, L) Intestinal lamina propria cells were analyzed by flow cytometry for the ratio of ILC2/ILCs and IL-13 + ILC2/ILC2 in WT mice (n = 3-4). (M, N) IL-13 immunohistochemical staining and intensity quantification analysis in the ileum, scale bar is 100 μm (n = 8). The results are expressed as the mean ± SEM (B, C, E–J, N) . * p < 0.05, ** p < 0.01, *** p < 0.001, NS means No statistically significant difference by one-way ANOVA (Tukey’s test). PA, pravastatin; I/R, ischemia/reperfusion; ILC2, type II innate lymphoid cells.

    Journal: Frontiers in Immunology

    Article Title: Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL−33/ST2 Signaling

    doi: 10.3389/fimmu.2021.704836

    Figure Lengend Snippet: PA protected against intestinal I/R injury via an IL-33/ST2 signal. (A) IL-33 immunohistochemical staining in the ileum from sham, I/R and I/R + PA mice, scale bar is 100 μm (n = 8). (B, C) Relative mRNA levels of IL-33 and IL-33 receptor (ST2) (n = 8). (D) HE staining, ZO-1, Occludin and Ki67 immunofluorescent staining and IL-33 immunohistochemical staining in WT mice and IL-33 -/- mice, scale bar is 100 μm (n = 8). (E) Pathological damage score in the ileum. (F–H) The relative fluorescence intensity quantification analysis of ZO-1, Occludin and Ki67 in the ileum. (I) The relative mRNA level of Lgr5 in the ileum was measured by quantitative PCR (n = 8). (J) The relative IL-33 intensity quantification analysis in the ileum. (K, L) Intestinal lamina propria cells were analyzed by flow cytometry for the ratio of ILC2/ILCs and IL-13 + ILC2/ILC2 in WT mice (n = 3-4). (M, N) IL-13 immunohistochemical staining and intensity quantification analysis in the ileum, scale bar is 100 μm (n = 8). The results are expressed as the mean ± SEM (B, C, E–J, N) . * p < 0.05, ** p < 0.01, *** p < 0.001, NS means No statistically significant difference by one-way ANOVA (Tukey’s test). PA, pravastatin; I/R, ischemia/reperfusion; ILC2, type II innate lymphoid cells.

    Article Snippet: The cell surface was stained using APC-Cyanine7-conjugated CD45 Antibody (Cat# A15395, eBioscience), FITC-conjugated mouse Hematopoietic Lineage Antibody Cocktail (Cat# 22-7770-72, eBioscience), and BV421-conjugated Rat Anti-Mouse IL-33R (ST2) antibody (Cat# 566309, BD Biosciences, San Jose, CA, USA).

    Techniques: Immunohistochemical staining, Staining, Fluorescence, Real-time Polymerase Chain Reaction, Flow Cytometry